Target organ toxins are chemicals that can cause adverse effects or disease states manifested in specific organs of the body toxins do not affect all organs in the body to the same extent due to their different cell structures. Target organ effects indicate which bodily organs are most likely to be affected by exposure to a substance casarett and doulls toxicology the basic science of poisons states that most chemicals that produce systemic toxicity do not cause a similar degree of toxicity in all organs but usually produce the major toxicity to one or two organs. Note the specific target organ organ system that has been primarily affected by the classified substance shall be identified where possible and where this is not possible the substance shall be identified as a general toxicant. Chapter 13 specific target organ systemic toxicity tost following repeated exposure definitions 1 classification identifies the chemical substance as being a specific target organ systemic toxicant
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